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The concomitant usage of METHADOSE with all cytochrome P450 3A4, 2B6, 2C19, 2C9 or 2D6 inhibitors may well end in an increase in methadone plasma concentrations, which could cause likely lethal respiratory depression. On top of that, discontinuation of concomitantly utilized cytochrome P450 3A4, 2B6, 2C19, or 2C9 inducers might also bring about a r

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